Dementia-Brain MRI protocol


  • Sag SE T1 
  • Ax Fr-FSE T2 
  • Ax Flair 
  • Cor Obl T2 (temporal lobes)
  • Cor Obl TIR (temporal lobes)
  • Ax DWI 
  • Ax EPI-GRE 


FLAIR images are used to assess global cortical atrophy (GCA), vascular white matter hyperintensities and infarctions.

T2-weighted images are used to assess infarctions, in particular lacunar infarctions in the thalamus and basal ganglia, which can be missed on FLAIR images.

T2*-weighted images are necessary to detect microbleeds in amyloid angiopathy. These images can also depict calcifications and iron deposition.

DWI should be considered as a supplemental sequence in young patients or in rapidly progressive neurodegenerative disorders (DD - vasculitis, CJD).


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