Imaging of Cerebral Abscess by MRI Perfusion

pMRI can help in differentiating abscess from necrotic neoplasm.This is a rapid acquisition with moderate spatial resolution that can yield information on the entire brain and multiple lesions, even in agitated patients. 
This sequence must be the first sequence performed after the gadolinium injection, and is acquired dynamically. After a baseline brain image acquisition is performed, an injection time of <8 sec is used to deliver 0.2 mmol/kg gadolinium chelate with a 10 ml normal saline bolus flush via the injector. This step may be performed by hand, but timing of the sequence is problematic. 
Perform image analysis visually or off-line on a workstation using commercially available programs. 
Regional cerebral blood volume (rCBV) maps can be reconstructed using an appropriate analysis of the MR signal intensity as a function of time. 
The rCBV maps can be aligned with the anatomic images to obtain region-of-interest (ROI) data.