Pulse sequences used for MR imaging of the spleen are similar to those used for standard abdominal MR imaging. Our standard protocol comprises the following sequences:
- Coronal T2-weighted half-Fourier rapid acquisition with relaxation enhancement (RARE) imaging
- Axial turbo/fast spin-echo T2-weighted or long echo time inversion-recovery imaging performed during a breath hold
- Axial gradient-echo (GRE) T1-weighted chemical shift in-phase and out-of-phase imaging performed during a breath hold
- Axial three-dimensional (3D) GRE breath-hold sequence such as volumetric interpolated breath-hold examination (VIBE) with pre-contrast and dynamic gadolinium-enhanced imaging.
The MR imaging characteristics of the spleen are unique with a large fractional heme content characterized by long T1 and T2 (lower in signal intensity than the liver on T1-weighted images and higher on T2-weighted images) . Images obtained immediately after gadolinium enhancement usually demonstrate different circulations as regions of alternating high and low signal intensity, resulting in a serpentine or arciform pattern . This pattern becomes homogeneous approximately 60–90 seconds after contrast material administration.
Axial 3D GRE VIBE image obtained immediately after administration of contrast material shows the arciform normal enhancement pattern of the spleen. |
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