Seizure/Epilepsy MRI Protocol


Without contrast "Seizure/Epilepsy MRI Protocol"

  • Sag T1 Brain  MPRAGE
  • Oblique Coronal 3D SPGR   1.6-mm (Temporal lobe)
  • Oblique Coronal True IR 4mm (Temporal lobe)
  • Axial FLAIR Brain 
  • Axial T2/PD Brain
  • Axial GRE 
  • Coronal FLAIR/ T2
  • Axial DWI + ADC
Post Contrast "Seizure/Epilepsy MRI Protocol"
  • Axial T1 
  • 1H Magnetic resonance spectroscopy and dynamic susceptibility contrast MRI
Optional "Seizure/Epilepsy MRI Protocol"

New-onset seizures:            Routine brain with contrast

                                                  Axial gradient-recalled echo (GRE) T2∗



   Recurrent seizures:           Noncontrast MRI study

Technical notes "Seizure/Epilepsy MRI Protocol"
  •  TIR (True IR)is ideally suited to identify signal changes in the hippocampus, since gliotic changes have increased water content appearing as increased signal on T2-weighted MRI. 
  • The TIRsequence nulls the increased signal intensity of the cerebrospinal fluid (CSF) in the temporal horn of the lateral ventricle and the choroidal fissure that can dwarf the increased signal in the hippocampus on a conventional thin-slice T2-weighted spin echo image.

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